Biologic Effects of Platelet-Derived Growth Factor Receptor α Blockade in Uterine Cancer
نویسندگان
چکیده
منابع مشابه
Biologic effects of platelet-derived growth factor receptor α blockade in uterine cancer.
PURPOSE Platelet-derived growth factor receptor α (PDGFRα) expression is frequently observed in many kinds of cancer and is a candidate for therapeutic targeting. This preclinical study evaluated the biologic significance of PDGFRα and PDGFRα blockade (using a fully humanized monoclonal antibody, 3G3) in uterine cancer. EXPERIMENTAL DESIGN Expression of PDGFRα was examined in uterine cancer c...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2014
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-13-2507